L371-0118 Screening compound: 4-{[(4-chlorophenyl)methyl]amino}-3-methyl-N-[(5-methylfuran-2-yl)methyl]-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

L371-0118 Screening compound: 4-{[(4-chlorophenyl)methyl]amino}-3-methyl-N-[(5-methylfuran-2-yl)methyl]-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
L371-0118 Screening compound: 4-{[(4-chlorophenyl)methyl]amino}-3-methyl-N-[(5-methylfuran-2-yl)methyl]-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L371-0118
4-{[(4-chlorophenyl)methyl]amino}-3-methyl-N-[(5-methylfuran-2-yl)methyl]-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L371-0118

Molecular Formula

C27H24ClN5O2 (C27 H24 ClN5 O2)

Compound Name

4-{[(4-chlorophenyl)methyl]amino}-3-methyl-N-[(5-methylfuran-2-yl)methyl]-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

IUPAC name

4-{[(4-chlorophenyl)methyl]amino}-3-methyl-N-[(5-methylfuran-2-yl)methyl]-1-phenyl-1H-pyrazolo[34-b]pyridine-5-carboxamide

SMILES

Cc1ccc(CNC(c(cnc2c3c(C)nn2-c2ccccc2)c3NCc(cc2)ccc2Cl)=O)o1

InChI

InChI=1S/C27H24ClN5O2/c1-17-8-13-22(35-17)15-31-27(34)23-16-30-26-24(18(2)32-33(26)21-6-4-3-5-7-21)25(23)29-14-19-9-11-20(28)12-10-19/h3-13,16H,14-15H2,1-2H3,(H,29,30)(H,31,34)

InChI Key

DPQHGWAHQNWDCP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15125491

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.97

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.740

Distribution Coefficient, logD

4.725

Water Solubility, LogSw

-4.91

Polar Surface Area

64.671

Acid Dissociation Constant (pKa)

12.45

Base Dissociation Constant (pKb)

5.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.80

L371-0118 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Glucocorticoid receptors Library (4806 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Proteases
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L371-0118 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L371-0118?
Check Price and Availability of L371-0118, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L371-0118 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L371-0118
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L371-0118
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L371-0118 available by request