L371-2495 Screening compound: [4-(2,3-dimethylphenyl)piperazino][1,3-dimethyl-4-(4-toluidino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methanone

L371-2495 Screening compound: [4-(2,3-dimethylphenyl)piperazino][1,3-dimethyl-4-(4-toluidino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methanone
L371-2495 Screening compound: [4-(2,3-dimethylphenyl)piperazino][1,3-dimethyl-4-(4-toluidino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound L371-2495
[4-(2,3-dimethylphenyl)piperazino][1,3-dimethyl-4-(4-toluidino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L371-2495

Molecular Formula

C28H32N6O (C28 H32 N6 O)

Compound Name

[4-(2,3-dimethylphenyl)piperazino][1,3-dimethyl-4-(4-toluidino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methanone

IUPAC name

5-[4-(23-dimethylphenyl)piperazine-1-carbonyl]-13-dimethyl-N-(4-methylphenyl)-1H-pyrazolo[34-b]pyridin-4-amine

SMILES

Cc1nn(C)c(nc2)c1c(Nc1ccc(C)cc1)c2C(N(CC1)CCN1c1c(C)c(C)ccc1)=O

InChI

InChI=1S/C28H32N6O/c1-18-9-11-22(12-10-18)30-26-23(17-29-27-25(26)21(4)31-32(27)5)28(35)34-15-13-33(14-16-34)24-8-6-7-19(2)20(24)3/h6-12,17H,13-16H2,1-5H3,(H,29,30)

InChI Key

PGRSRZFAPCGTJD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642024

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.6

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.355

Distribution Coefficient, logD

4.351

Water Solubility, LogSw

-4.37

Polar Surface Area

51.702

Acid Dissociation Constant (pKa)

15.31

Base Dissociation Constant (pKb)

5.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.14

L371-2495 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L371-2495 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L371-2495?
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What is the minimum amount of L371-2495 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L371-2495
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L371-2495
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L371-2495 available by request