L371-2760 Screening compound: 4-{[(4-chlorophenyl)methyl]amino}-3-methyl-1-phenyl-N-[3-(pyrrolidin-1-yl)propyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

L371-2760 Screening compound: 4-{[(4-chlorophenyl)methyl]amino}-3-methyl-1-phenyl-N-[3-(pyrrolidin-1-yl)propyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
L371-2760 Screening compound: 4-{[(4-chlorophenyl)methyl]amino}-3-methyl-1-phenyl-N-[3-(pyrrolidin-1-yl)propyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L371-2760
4-{[(4-chlorophenyl)methyl]amino}-3-methyl-1-phenyl-N-[3-(pyrrolidin-1-yl)propyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L371-2760

Molecular Formula

C28H31ClN6O (C28 H31 ClN6 O)

Compound Name

4-{[(4-chlorophenyl)methyl]amino}-3-methyl-1-phenyl-N-[3-(pyrrolidin-1-yl)propyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

IUPAC name

4-{[(4-chlorophenyl)methyl]amino}-3-methyl-1-phenyl-N-[3-(pyrrolidin-1-yl)propyl]-1H-pyrazolo[34-b]pyridine-5-carboxamide

SMILES

Cc(c1c2ncc(C(NCCCN3CCCC3)=O)c1NCc(cc1)ccc1Cl)nn2-c1ccccc1

InChI

InChI=1S/C28H31ClN6O/c1-20-25-26(31-18-21-10-12-22(29)13-11-21)24(28(36)30-14-7-17-34-15-5-6-16-34)19-32-27(25)35(33-20)23-8-3-2-4-9-23/h2-4,8-13,19H,5-7,14-18H2,1H3,(H,30,36)(H,31,32)

InChI Key

IBYWHWBAKUYWJQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15125511

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

503.05

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.620

Distribution Coefficient, logD

0.588

Water Solubility, LogSw

-4.05

Polar Surface Area

61.598

Acid Dissociation Constant (pKa)

14.49

Base Dissociation Constant (pKb)

10.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.10

L371-2760 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Glucocorticoid receptors Library (4806 compounds)

Antibacterial Compounds Library (13827 compounds)

Epigenetics Focused Set (26518 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Infections
  • Immune system
  • animal
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Proteases
  • Nuclear receptors
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L371-2760 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L371-2760?
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What is the minimum amount of L371-2760 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L371-2760
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L371-2760
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L371-2760 available by request