L383-1442 Screening compound: 2-({6-[4-(3-methylphenyl)piperazin-1-yl]pyridazin-3-yl}sulfanyl)-1-(4-phenylpiperazin-1-yl)ethan-1-one

L383-1442 Screening compound: 2-({6-[4-(3-methylphenyl)piperazin-1-yl]pyridazin-3-yl}sulfanyl)-1-(4-phenylpiperazin-1-yl)ethan-1-one
L383-1442 Screening compound: 2-({6-[4-(3-methylphenyl)piperazin-1-yl]pyridazin-3-yl}sulfanyl)-1-(4-phenylpiperazin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L383-1442
2-({6-[4-(3-methylphenyl)piperazin-1-yl]pyridazin-3-yl}sulfanyl)-1-(4-phenylpiperazin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L383-1442

Molecular Formula

C27H32N6OS (C27 H32 N6 OS)

Compound Name

2-({6-[4-(3-methylphenyl)piperazin-1-yl]pyridazin-3-yl}sulfanyl)-1-(4-phenylpiperazin-1-yl)ethan-1-one

IUPAC name

2-({6-[4-(3-methylphenyl)piperazin-1-yl]pyridazin-3-yl}sulfanyl)-1-(4-phenylpiperazin-1-yl)ethan-1-one

SMILES

Cc1cccc(N(CC2)CCN2c(cc2)nnc2SCC(N(CC2)CCN2c2ccccc2)=O)c1

InChI

InChI=1S/C27H32N6OS/c1-22-6-5-9-24(20-22)31-12-16-32(17-13-31)25-10-11-26(29-28-25)35-21-27(34)33-18-14-30(15-19-33)23-7-3-2-4-8-23/h2-11,20H,12-19,21H2,1H3

InChI Key

SKLSUXKENPPMKK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27249152

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.66

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.347

Distribution Coefficient, logD

4.346

Water Solubility, LogSw

-4.30

Polar Surface Area

46.900

Acid Dissociation Constant (pKa)

21.51

Base Dissociation Constant (pKb)

3.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.00

L383-1442 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L383-1442 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L383-1442?
Check Price and Availability of L383-1442, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L383-1442 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L383-1442
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L383-1442
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L383-1442 available by request