L387-6312 Screening compound: 5-{[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]sulfanyl}-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

L387-6312 Screening compound: 5-{[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]sulfanyl}-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
L387-6312 Screening compound: 5-{[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]sulfanyl}-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L387-6312
5-{[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]sulfanyl}-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L387-6312

Molecular Formula

C24H27N5O2S2 (C24 H27 N5 O2 S2)

Compound Name

5-{[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]sulfanyl}-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

5-{[2-oxo-2-(1234-tetrahydroisoquinolin-2-yl)ethyl]sulfanyl}-2-(piperidin-1-yl)-6-(prop-2-en-1-yl)-6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

C=CCN(C1=O)C(SCC(N(CC2)Cc3c2cccc3)=O)=Nc2c1sc(N1CCCCC1)n2

InChI

InChI=1S/C24H27N5O2S2/c1-2-11-29-22(31)20-21(25-23(33-20)27-12-6-3-7-13-27)26-24(29)32-16-19(30)28-14-10-17-8-4-5-9-18(17)15-28/h2,4-5,8-9H,1,3,6-7,10-16H2

InChI Key

SQWPVZIFXLVPCB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27644640

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.64

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.536

Distribution Coefficient, logD

4.536

Water Solubility, LogSw

-4.24

Polar Surface Area

55.924

Acid Dissociation Constant (pKa)

22.98

Base Dissociation Constant (pKb)

-2.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

References: we are preparing a list of scientific research reports with L387-6312 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L387-6312?
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What is the minimum amount of L387-6312 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L387-6312
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L387-6312
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L387-6312 available by request