L390-0146 Screening compound: 1-(3-chlorophenyl)-4-{7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl}piperazine

L390-0146 Screening compound: 1-(3-chlorophenyl)-4-{7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl}piperazine
L390-0146 Screening compound: 1-(3-chlorophenyl)-4-{7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L390-0146
1-(3-chlorophenyl)-4-{7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L390-0146

Molecular Formula

C23H20ClN5O (C23 H20 ClN5 O)

Compound Name

1-(3-chlorophenyl)-4-{7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl}piperazine

IUPAC name

1-(3-chlorophenyl)-4-{7-phenylpyrazolo[15-a]pyrimidine-3-carbonyl}piperazine

SMILES

O=C(c1c2nccc(-c3ccccc3)n2nc1)N(CC1)CCN1c1cccc(Cl)c1

InChI

InChI=1S/C23H20ClN5O/c24-18-7-4-8-19(15-18)27-11-13-28(14-12-27)23(30)20-16-26-29-21(9-10-25-22(20)29)17-5-2-1-3-6-17/h1-10,15-16H,11-14H2

InChI Key

UMYOBXVSFADAHT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD13350337

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.869

Distribution Coefficient, logD

3.869

Water Solubility, LogSw

-4.26

Polar Surface Area

39.508

Acid Dissociation Constant (pKa)

27.18

Base Dissociation Constant (pKb)

1.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

L390-0146 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with L390-0146 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L390-0146?
Check Price and Availability of L390-0146, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L390-0146 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L390-0146
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L390-0146
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L390-0146 available by request