L390-1440 Screening compound: 2-{4-[7-(4-ethoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazin-1-yl}-N-(4-methylphenyl)acetamide

L390-1440 Screening compound: 2-{4-[7-(4-ethoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazin-1-yl}-N-(4-methylphenyl)acetamide
L390-1440 Screening compound: 2-{4-[7-(4-ethoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazin-1-yl}-N-(4-methylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L390-1440
2-{4-[7-(4-ethoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazin-1-yl}-N-(4-methylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L390-1440

Molecular Formula

C28H30N6O3 (C28 H30 N6 O3)

Compound Name

2-{4-[7-(4-ethoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazin-1-yl}-N-(4-methylphenyl)acetamide

IUPAC name

2-{4-[7-(4-ethoxyphenyl)pyrazolo[15-a]pyrimidine-3-carbonyl]piperazin-1-yl}-N-(4-methylphenyl)acetamide

SMILES

CCOc(cc1)ccc1-c(n1nc2)ccnc1c2C(N1CCN(CC(Nc2ccc(C)cc2)=O)CC1)=O

InChI

InChI=1S/C28H30N6O3/c1-3-37-23-10-6-21(7-11-23)25-12-13-29-27-24(18-30-34(25)27)28(36)33-16-14-32(15-17-33)19-26(35)31-22-8-4-20(2)5-9-22/h4-13,18H,3,14-17,19H2,1-2H3,(H,31,35)

InChI Key

SMZSYKMWYVWJHX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27250579

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.58

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.926

Distribution Coefficient, logD

3.926

Water Solubility, LogSw

-3.67

Polar Surface Area

70.062

Acid Dissociation Constant (pKa)

12.46

Base Dissociation Constant (pKb)

3.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L390-1440 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Immunological Library (6760 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with L390-1440 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L390-1440?
Check Price and Availability of L390-1440, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L390-1440 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L390-1440
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L390-1440
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L390-1440 available by request