L418-0149 Screening compound: ethyl 3-({5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carbonyl}amino)propanoate

L418-0149 Screening compound: ethyl 3-({5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carbonyl}amino)propanoate
L418-0149 Screening compound: ethyl 3-({5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carbonyl}amino)propanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L418-0149
ethyl 3-({5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carbonyl}amino)propanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L418-0149

Molecular Formula

C25H29N3O5 (C25 H29 N3 O5)

Compound Name

ethyl 3-({5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carbonyl}amino)propanoate

IUPAC name

ethyl 3-({5-[4-(morpholine-4-carbonyl)phenyl]-23-dihydro-1H-indole-1-carbonyl}amino)propanoate

SMILES

CCOC(CCNC(N(CC1)c(cc2)c1cc2-c(cc1)ccc1C(N1CCOCC1)=O)=O)=O

InChI

InChI=1S/C25H29N3O5/c1-2-33-23(29)9-11-26-25(31)28-12-10-21-17-20(7-8-22(21)28)18-3-5-19(6-4-18)24(30)27-13-15-32-16-14-27/h3-8,17H,2,9-16H2,1H3,(H,26,31)

InChI Key

YGJVRKLHBAFZPY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15126851

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.831

Distribution Coefficient, logD

2.831

Water Solubility, LogSw

-3.44

Polar Surface Area

70.617

Acid Dissociation Constant (pKa)

15.55

Base Dissociation Constant (pKb)

-0.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

L418-0149 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Bromodomain Modulators Library (5801 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L418-0149 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L418-0149?
Check Price and Availability of L418-0149, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L418-0149 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L418-0149
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L418-0149
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L418-0149 available by request