L426-3127 Screening compound: N-METHYL-N'-(4-{1-[(4-PHENYLPIPERAZINO)CARBONYL]CYCLOBUTYL}PHENYL)UREA

L426-3127 Screening compound: N-METHYL-N'-(4-{1-[(4-PHENYLPIPERAZINO)CARBONYL]CYCLOBUTYL}PHENYL)UREA
L426-3127 Screening compound: N-METHYL-N'-(4-{1-[(4-PHENYLPIPERAZINO)CARBONYL]CYCLOBUTYL}PHENYL)UREA alternative view

Chemical Structure Depiction of ChemDiv screening compound L426-3127
N-METHYL-N'-(4-{1-[(4-PHENYLPIPERAZINO)CARBONYL]CYCLOBUTYL}PHENYL)UREA

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L426-3127

Molecular Formula

C23H28N4O2 (C23 H28 N4 O2)

Compound Name

N-METHYL-N'-(4-{1-[(4-PHENYLPIPERAZINO)CARBONYL]CYCLOBUTYL}PHENYL)UREA

IUPAC name

3-methyl-1-{4-[1-(4-phenylpiperazine-1-carbonyl)cyclobutyl]phenyl}urea

SMILES

CNC(Nc1ccc(C2(CCC2)C(N(CC2)CCN2c2ccccc2)=O)cc1)=O

InChI

InChI=1S/C23H28N4O2/c1-24-22(29)25-19-10-8-18(9-11-19)23(12-5-13-23)21(28)27-16-14-26(15-17-27)20-6-3-2-4-7-20/h2-4,6-11H,5,12-17H2,1H3,(H2,24,25,29)

InChI Key

WXTDRYYCKHFCLH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27252200

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.001

Distribution Coefficient, logD

3.001

Water Solubility, LogSw

-3.51

Polar Surface Area

54.446

Acid Dissociation Constant (pKa)

13.51

Base Dissociation Constant (pKb)

3.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.13

L426-3127 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L426-3127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L426-3127?
Check Price and Availability of L426-3127, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L426-3127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L426-3127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L426-3127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L426-3127 available by request