L428-0808 Screening compound: N-(3-chloro-4-fluorophenyl)-5-(4-methoxyphenyl)pyridine-3-carboxamide

L428-0808 Screening compound: N-(3-chloro-4-fluorophenyl)-5-(4-methoxyphenyl)pyridine-3-carboxamide
L428-0808 Screening compound: N-(3-chloro-4-fluorophenyl)-5-(4-methoxyphenyl)pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L428-0808
N-(3-chloro-4-fluorophenyl)-5-(4-methoxyphenyl)pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L428-0808

Molecular Formula

C19H14ClFN2O2 (C19 H14 ClFN2 O2)

Compound Name

N-(3-chloro-4-fluorophenyl)-5-(4-methoxyphenyl)pyridine-3-carboxamide

IUPAC name

N-(3-chloro-4-fluorophenyl)-5-(4-methoxyphenyl)pyridine-3-carboxamide

SMILES

COc(cc1)ccc1-c1cc(C(Nc(cc2)cc(Cl)c2F)=O)cnc1

InChI

InChI=1S/C19H14ClFN2O2/c1-25-16-5-2-12(3-6-16)13-8-14(11-22-10-13)19(24)23-15-4-7-18(21)17(20)9-15/h2-11H,1H3,(H,23,24)

InChI Key

SCZUVIJIKBXUQL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27252301

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.78

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.522

Distribution Coefficient, logD

4.341

Water Solubility, LogSw

-4.73

Polar Surface Area

40.209

Acid Dissociation Constant (pKa)

7.69

Base Dissociation Constant (pKb)

2.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

L428-0808 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Akt-Targeted Library (14764 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Proteases
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L428-0808 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L428-0808?
Check Price and Availability of L428-0808, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L428-0808 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L428-0808
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L428-0808
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L428-0808 available by request