L445-0298 Screening compound: N-cyclohexyl-1-[4-(3-methoxybenzenesulfonamido)benzoyl]piperidine-4-carboxamide

L445-0298 Screening compound: N-cyclohexyl-1-[4-(3-methoxybenzenesulfonamido)benzoyl]piperidine-4-carboxamide
L445-0298 Screening compound: N-cyclohexyl-1-[4-(3-methoxybenzenesulfonamido)benzoyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L445-0298
N-cyclohexyl-1-[4-(3-methoxybenzenesulfonamido)benzoyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L445-0298

Molecular Formula

C26H33N3O5S (C26 H33 N3 O5 S)

Compound Name

N-cyclohexyl-1-[4-(3-methoxybenzenesulfonamido)benzoyl]piperidine-4-carboxamide

IUPAC name

N-cyclohexyl-1-[4-(3-methoxybenzenesulfonamido)benzoyl]piperidine-4-carboxamide

SMILES

COc1cccc(S(Nc(cc2)ccc2C(N(CC2)CCC2C(NC2CCCCC2)=O)=O)(=O)=O)c1

InChI

InChI=1S/C26H33N3O5S/c1-34-23-8-5-9-24(18-23)35(32,33)28-22-12-10-20(11-13-22)26(31)29-16-14-19(15-17-29)25(30)27-21-6-3-2-4-7-21/h5,8-13,18-19,21,28H,2-4,6-7,14-17H2,1H3,(H,27,30)

InChI Key

QWBDGDNHENSQAT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15127771

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

499.63

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.217

Distribution Coefficient, logD

2.753

Water Solubility, LogSw

-3.64

Polar Surface Area

89.219

Acid Dissociation Constant (pKa)

7.12

Base Dissociation Constant (pKb)

1.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

L445-0298 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L445-0298 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L445-0298?
Check Price and Availability of L445-0298, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L445-0298 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L445-0298
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L445-0298
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L445-0298 available by request