L454-0222 Screening compound: N~3~-(5-chloro-2-methoxyphenyl)-6-(4-fluorophenyl)nicotinamide

L454-0222 Screening compound: N~3~-(5-chloro-2-methoxyphenyl)-6-(4-fluorophenyl)nicotinamide
L454-0222 Screening compound: N~3~-(5-chloro-2-methoxyphenyl)-6-(4-fluorophenyl)nicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L454-0222
N~3~-(5-chloro-2-methoxyphenyl)-6-(4-fluorophenyl)nicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L454-0222

Molecular Formula

C19H14ClFN2O2 (C19 H14 ClFN2 O2)

Compound Name

N~3~-(5-chloro-2-methoxyphenyl)-6-(4-fluorophenyl)nicotinamide

IUPAC name

n/a

SMILES

COc(ccc(Cl)c1)c1NC(c(cc1)cnc1-c(cc1)ccc1F)=O

InChI

InChI=1S/C19H14ClFN2O2/c1-25-18-9-5-14(20)10-17(18)23-19(24)13-4-8-16(22-11-13)12-2-6-15(21)7-3-12/h2-11H,1H3,(H,23,24)

InChI Key

ONJKGXXAHWPSBN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27253362

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.78

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.706

Distribution Coefficient, logD

4.504

Water Solubility, LogSw

-4.92

Polar Surface Area

39.128

Acid Dissociation Constant (pKa)

7.63

Base Dissociation Constant (pKb)

2.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

References: we are preparing a list of scientific research reports with L454-0222 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L454-0222?
Check Price and Availability of L454-0222, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L454-0222 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L454-0222
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L454-0222
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L454-0222 available by request