L457-0119 Screening compound: 1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-4-carbonyl]piperazine

L457-0119 Screening compound: 1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-4-carbonyl]piperazine
L457-0119 Screening compound: 1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-4-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L457-0119
1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-4-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L457-0119

Molecular Formula

C22H28N4O2 (C22 H28 N4 O2)

Compound Name

1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-4-carbonyl]piperazine

IUPAC name

1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-4-carbonyl]piperazine

SMILES

COc(cc1)ccc1N(CC1)CCN1C(C(CC1)CCN1c1ccncc1)=O

InChI

InChI=1S/C22H28N4O2/c1-28-21-4-2-19(3-5-21)25-14-16-26(17-15-25)22(27)18-8-12-24(13-9-18)20-6-10-23-11-7-20/h2-7,10-11,18H,8-9,12-17H2,1H3

InChI Key

ROAWHOPBQRIVKC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128016

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.540

Distribution Coefficient, logD

1.936

Water Solubility, LogSw

-2.18

Polar Surface Area

40.572

Acid Dissociation Constant (pKa)

22.83

Base Dissociation Constant (pKb)

7.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.50

L457-0119 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L457-0119 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L457-0119?
Check Price and Availability of L457-0119, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L457-0119 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L457-0119
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L457-0119
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L457-0119 available by request