L457-0175 Screening compound: N-[(2-fluorophenyl)methyl]-1-(pyridin-4-yl)piperidine-4-carboxamide

L457-0175 Screening compound: N-[(2-fluorophenyl)methyl]-1-(pyridin-4-yl)piperidine-4-carboxamide
L457-0175 Screening compound: N-[(2-fluorophenyl)methyl]-1-(pyridin-4-yl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L457-0175
N-[(2-fluorophenyl)methyl]-1-(pyridin-4-yl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L457-0175

Molecular Formula

C18H20FN3O (C18 H20 FN3 O)

Compound Name

N-[(2-fluorophenyl)methyl]-1-(pyridin-4-yl)piperidine-4-carboxamide

IUPAC name

N-[(2-fluorophenyl)methyl]-1-(pyridin-4-yl)piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1ccncc1)NCc(cccc1)c1F

InChI

InChI=1S/C18H20FN3O/c19-17-4-2-1-3-15(17)13-21-18(23)14-7-11-22(12-8-14)16-5-9-20-10-6-16/h1-6,9-10,14H,7-8,11-13H2,(H,21,23)

InChI Key

SUAUNULIJKVILB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128043

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

313.37

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.262

Distribution Coefficient, logD

1.658

Water Solubility, LogSw

-2.25

Polar Surface Area

37.532

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

7.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L457-0175 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds
Targets:
  • Others
  • Ion Channels

References: we are preparing a list of scientific research reports with L457-0175 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L457-0175?
Check Price and Availability of L457-0175, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L457-0175 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L457-0175
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L457-0175
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L457-0175 available by request