L464-0470 Screening compound: 5-(3,4-dimethyl-1,2-oxazol-5-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide

L464-0470 Screening compound: 5-(3,4-dimethyl-1,2-oxazol-5-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide
L464-0470 Screening compound: 5-(3,4-dimethyl-1,2-oxazol-5-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L464-0470
5-(3,4-dimethyl-1,2-oxazol-5-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L464-0470

Molecular Formula

C15H15N3O5S3 (C15 H15 N3 O5 S3)

Compound Name

5-(3,4-dimethyl-1,2-oxazol-5-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide

IUPAC name

5-(34-dimethyl-12-oxazol-5-yl)-N-(4-sulfamoylphenyl)thiophene-2-sulfonamide

SMILES

Cc1c(-c(s2)ccc2S(Nc(cc2)ccc2S(N)(=O)=O)(=O)=O)onc1C

InChI

InChI=1S/C15H15N3O5S3/c1-9-10(2)17-23-15(9)13-7-8-14(24-13)26(21,22)18-11-3-5-12(6-4-11)25(16,19)20/h3-8,18H,1-2H3,(H2,16,19,20)

InChI Key

QNERMCSBZBBZDQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27254527

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.5

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.433

Distribution Coefficient, logD

1.788

Water Solubility, LogSw

-2.94

Polar Surface Area

114.855

Acid Dissociation Constant (pKa)

6.87

Base Dissociation Constant (pKb)

-0.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.30

L464-0470 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Carbonic Anhydrase II Library (4939 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L464-0470 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L464-0470?
Check Price and Availability of L464-0470, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L464-0470 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L464-0470
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L464-0470
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L464-0470 available by request