L471-2421 Screening compound: 2-(1H-indol-3-yl)-1-(4-{3-[4-(piperidin-1-yl)phenyl]-1,2,4-oxadiazole-5-carbonyl}piperazin-1-yl)ethan-1-one

L471-2421 Screening compound: 2-(1H-indol-3-yl)-1-(4-{3-[4-(piperidin-1-yl)phenyl]-1,2,4-oxadiazole-5-carbonyl}piperazin-1-yl)ethan-1-one
L471-2421 Screening compound: 2-(1H-indol-3-yl)-1-(4-{3-[4-(piperidin-1-yl)phenyl]-1,2,4-oxadiazole-5-carbonyl}piperazin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L471-2421
2-(1H-indol-3-yl)-1-(4-{3-[4-(piperidin-1-yl)phenyl]-1,2,4-oxadiazole-5-carbonyl}piperazin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L471-2421

Molecular Formula

C28H30N6O3 (C28 H30 N6 O3)

Compound Name

2-(1H-indol-3-yl)-1-(4-{3-[4-(piperidin-1-yl)phenyl]-1,2,4-oxadiazole-5-carbonyl}piperazin-1-yl)ethan-1-one

IUPAC name

2-(1H-indol-3-yl)-1-(4-{3-[4-(piperidin-1-yl)phenyl]-124-oxadiazole-5-carbonyl}piperazin-1-yl)ethan-1-one

SMILES

O=C(Cc1c[nH]c2c1cccc2)N(CC1)CCN1C(c1nc(-c(cc2)ccc2N2CCCCC2)no1)=O

InChI

InChI=1S/C28H30N6O3/c35-25(18-21-19-29-24-7-3-2-6-23(21)24)33-14-16-34(17-15-33)28(36)27-30-26(31-37-27)20-8-10-22(11-9-20)32-12-4-1-5-13-32/h2-3,6-11,19,29H,1,4-5,12-18H2

InChI Key

FFTPEVGKWUAWPC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27454839

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.58

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.951

Distribution Coefficient, logD

3.951

Water Solubility, LogSw

-4.14

Polar Surface Area

77.816

Acid Dissociation Constant (pKa)

18.35

Base Dissociation Constant (pKb)

7.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.70

L471-2421 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Indole Derivatives (10091 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with L471-2421 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L471-2421?
Check Price and Availability of L471-2421, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L471-2421 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L471-2421
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L471-2421
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L471-2421 available by request