L471-2643 Screening compound: 1-(6-chloropyridine-3-carbonyl)-4-{3-[4-(4-methylpiperidin-1-yl)phenyl]-1,2,4-oxadiazole-5-carbonyl}piperazine

L471-2643 Screening compound: 1-(6-chloropyridine-3-carbonyl)-4-{3-[4-(4-methylpiperidin-1-yl)phenyl]-1,2,4-oxadiazole-5-carbonyl}piperazine
L471-2643 Screening compound: 1-(6-chloropyridine-3-carbonyl)-4-{3-[4-(4-methylpiperidin-1-yl)phenyl]-1,2,4-oxadiazole-5-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L471-2643
1-(6-chloropyridine-3-carbonyl)-4-{3-[4-(4-methylpiperidin-1-yl)phenyl]-1,2,4-oxadiazole-5-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L471-2643

Molecular Formula

C25H27ClN6O3 (C25 H27 ClN6 O3)

Compound Name

1-(6-chloropyridine-3-carbonyl)-4-{3-[4-(4-methylpiperidin-1-yl)phenyl]-1,2,4-oxadiazole-5-carbonyl}piperazine

IUPAC name

1-(6-chloropyridine-3-carbonyl)-4-{3-[4-(4-methylpiperidin-1-yl)phenyl]-124-oxadiazole-5-carbonyl}piperazine

SMILES

CC(CC1)CCN1c(cc1)ccc1-c1noc(C(N(CC2)CCN2C(c(cc2)cnc2Cl)=O)=O)n1

InChI

InChI=1S/C25H27ClN6O3/c1-17-8-10-30(11-9-17)20-5-2-18(3-6-20)22-28-23(35-29-22)25(34)32-14-12-31(13-15-32)24(33)19-4-7-21(26)27-16-19/h2-7,16-17H,8-15H2,1H3

InChI Key

USQUAGXLLHSMPP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27454869

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

494.98

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.337

Distribution Coefficient, logD

3.336

Water Solubility, LogSw

-3.61

Polar Surface Area

77.477

Acid Dissociation Constant (pKa)

25.52

Base Dissociation Constant (pKb)

3.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

L471-2643 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Eccentric PPI Library (11937 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Cyclic compounds
  • 3D
  • Fragments
  • Mimetics

References: we are preparing a list of scientific research reports with L471-2643 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L471-2643?
Check Price and Availability of L471-2643, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L471-2643 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L471-2643
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L471-2643
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L471-2643 available by request