L483-0681 Screening compound: ethyl 1-[1-(3-cyano-6-ethoxyquinolin-4-yl)piperidine-4-carbonyl]piperidine-4-carboxylate

L483-0681 Screening compound: ethyl 1-[1-(3-cyano-6-ethoxyquinolin-4-yl)piperidine-4-carbonyl]piperidine-4-carboxylate
L483-0681 Screening compound: ethyl 1-[1-(3-cyano-6-ethoxyquinolin-4-yl)piperidine-4-carbonyl]piperidine-4-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound L483-0681
ethyl 1-[1-(3-cyano-6-ethoxyquinolin-4-yl)piperidine-4-carbonyl]piperidine-4-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L483-0681

Molecular Formula

C26H32N4O4 (C26 H32 N4 O4)

Compound Name

ethyl 1-[1-(3-cyano-6-ethoxyquinolin-4-yl)piperidine-4-carbonyl]piperidine-4-carboxylate

IUPAC name

ethyl 1-[1-(3-cyano-6-ethoxyquinolin-4-yl)piperidine-4-carbonyl]piperidine-4-carboxylate

SMILES

CCOC(C(CC1)CCN1C(C(CC1)CCN1c(c1cc(OCC)ccc1nc1)c1C#N)=O)=O

InChI

InChI=1S/C26H32N4O4/c1-3-33-21-5-6-23-22(15-21)24(20(16-27)17-28-23)29-11-7-18(8-12-29)25(31)30-13-9-19(10-14-30)26(32)34-4-2/h5-6,15,17-19H,3-4,7-14H2,1-2H3

InChI Key

LSDFBXKHYWBWRW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27456602

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.56

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.413

Distribution Coefficient, logD

3.384

Water Solubility, LogSw

-3.49

Polar Surface Area

73.523

Acid Dissociation Constant (pKa)

22.83

Base Dissociation Constant (pKb)

6.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

53.80

L483-0681 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L483-0681 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L483-0681?
Check Price and Availability of L483-0681, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L483-0681 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L483-0681
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L483-0681
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L483-0681 available by request