L494-0157 Screening compound: N-(3-methoxyphenyl)-2-{3-[5-(piperidinomethyl)-1,3,4-oxadiazol-2-yl]-1H-indol-1-yl}acetamide

L494-0157 Screening compound: N-(3-methoxyphenyl)-2-{3-[5-(piperidinomethyl)-1,3,4-oxadiazol-2-yl]-1H-indol-1-yl}acetamide
L494-0157 Screening compound: N-(3-methoxyphenyl)-2-{3-[5-(piperidinomethyl)-1,3,4-oxadiazol-2-yl]-1H-indol-1-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L494-0157
N-(3-methoxyphenyl)-2-{3-[5-(piperidinomethyl)-1,3,4-oxadiazol-2-yl]-1H-indol-1-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L494-0157

Molecular Formula

C25H27N5O3 (C25 H27 N5 O3)

Compound Name

N-(3-methoxyphenyl)-2-{3-[5-(piperidinomethyl)-1,3,4-oxadiazol-2-yl]-1H-indol-1-yl}acetamide

IUPAC name

N-(3-methoxyphenyl)-2-(3-{5-[(piperidin-1-yl)methyl]-134-oxadiazol-2-yl}-1H-indol-1-yl)acetamide

SMILES

COc1cccc(NC(Cn2c(cccc3)c3c(-c3nnc(CN4CCCCC4)o3)c2)=O)c1

InChI

InChI=1S/C25H27N5O3/c1-32-19-9-7-8-18(14-19)26-23(31)16-30-15-21(20-10-3-4-11-22(20)30)25-28-27-24(33-25)17-29-12-5-2-6-13-29/h3-4,7-11,14-15H,2,5-6,12-13,16-17H2,1H3,(H,26,31)

InChI Key

RDQWYBISOJBPSK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128489

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.484

Distribution Coefficient, logD

3.471

Water Solubility, LogSw

-3.65

Polar Surface Area

66.578

Acid Dissociation Constant (pKa)

11.39

Base Dissociation Constant (pKb)

5.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L494-0157 in Drug Discovery

Included in Screening Libraries

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L494-0157 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L494-0157?
Check Price and Availability of L494-0157, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L494-0157 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L494-0157
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L494-0157
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L494-0157 available by request