L527-0250 Screening compound: 5-chloro-N~2~-[(3-cyclopropyl-3H-imidazo[4,5-b]pyridin-2-yl)methyl]-2-thiophenesulfonamide

L527-0250 Screening compound: 5-chloro-N~2~-[(3-cyclopropyl-3H-imidazo[4,5-b]pyridin-2-yl)methyl]-2-thiophenesulfonamide
L527-0250 Screening compound: 5-chloro-N~2~-[(3-cyclopropyl-3H-imidazo[4,5-b]pyridin-2-yl)methyl]-2-thiophenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L527-0250
5-chloro-N~2~-[(3-cyclopropyl-3H-imidazo[4,5-b]pyridin-2-yl)methyl]-2-thiophenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L527-0250

Molecular Formula

C14H13ClN4O2S2 (C14 H13 ClN4 O2 S2)

Compound Name

5-chloro-N~2~-[(3-cyclopropyl-3H-imidazo[4,5-b]pyridin-2-yl)methyl]-2-thiophenesulfonamide

IUPAC name

5-chloro-N-({3-cyclopropyl-3H-imidazo[45-b]pyridin-2-yl}methyl)thiophene-2-sulfonamide

SMILES

O=S(c(s1)ccc1Cl)(NCc(n1C2CC2)nc2c1nccc2)=O

InChI

InChI=1S/C14H13ClN4O2S2/c15-11-5-6-13(22-11)23(20,21)17-8-12-18-10-2-1-7-16-14(10)19(12)9-3-4-9/h1-2,5-7,9,17H,3-4,8H2

InChI Key

WJTRLFWTJCKXGP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459765

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.87

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.699

Distribution Coefficient, logD

2.464

Water Solubility, LogSw

-3.44

Polar Surface Area

64.734

Acid Dissociation Constant (pKa)

7.54

Base Dissociation Constant (pKb)

3.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.57

L527-0250 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Epigenetics Focused Set (26518 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L527-0250 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L527-0250?
Check Price and Availability of L527-0250, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L527-0250 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L527-0250
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L527-0250
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L527-0250 available by request