L527-0287 Screening compound: N~1~-{[3-(2-furylmethyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-3,4-dimethoxy-1-benzenesulfonamide

L527-0287 Screening compound: N~1~-{[3-(2-furylmethyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-3,4-dimethoxy-1-benzenesulfonamide
L527-0287 Screening compound: N~1~-{[3-(2-furylmethyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-3,4-dimethoxy-1-benzenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L527-0287
N~1~-{[3-(2-furylmethyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-3,4-dimethoxy-1-benzenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L527-0287

Molecular Formula

C20H20N4O5S (C20 H20 N4 O5 S)

Compound Name

N~1~-{[3-(2-furylmethyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-3,4-dimethoxy-1-benzenesulfonamide

IUPAC name

N-({3-[(furan-2-yl)methyl]-3H-imidazo[45-b]pyridin-2-yl}methyl)-34-dimethoxybenzene-1-sulfonamide

SMILES

COc(ccc(S(NCc(n1Cc2ccco2)nc2c1nccc2)(=O)=O)c1)c1OC

InChI

InChI=1S/C20H20N4O5S/c1-27-17-8-7-15(11-18(17)28-2)30(25,26)22-12-19-23-16-6-3-9-21-20(16)24(19)13-14-5-4-10-29-14/h3-11,22H,12-13H2,1-2H3

InChI Key

MKFGFGFAKYXDKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459786

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.47

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.307

Distribution Coefficient, logD

2.230

Water Solubility, LogSw

-2.81

Polar Surface Area

85.818

Acid Dissociation Constant (pKa)

8.11

Base Dissociation Constant (pKb)

3.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

L527-0287 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Immunological Library (6760 compounds)

Epigenetics Focused Set (26518 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L527-0287 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L527-0287?
Check Price and Availability of L527-0287, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L527-0287 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L527-0287
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L527-0287
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L527-0287 available by request