L532-2112 Screening compound: ethyl 2-{4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}acetate

L532-2112 Screening compound: ethyl 2-{4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}acetate
L532-2112 Screening compound: ethyl 2-{4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L532-2112
ethyl 2-{4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L532-2112

Molecular Formula

C22H29FN6O2S (C22 H29 FN6 O2 S)

Compound Name

ethyl 2-{4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}acetate

IUPAC name

ethyl 2-{4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[21-b][134]thiadiazol-2-yl]piperazin-1-yl}acetate

SMILES

CCOC(CN(CC1)CCN1c(s1)nn2c1nc(-c1cc(F)ccc1)c2NC(C)(C)C)=O

InChI

InChI=1S/C22H29FN6O2S/c1-5-31-17(30)14-27-9-11-28(12-10-27)21-26-29-19(25-22(2,3)4)18(24-20(29)32-21)15-7-6-8-16(23)13-15/h6-8,13,25H,5,9-12,14H2,1-4H3

InChI Key

FXFPOPHLZSTIPT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459966

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.084

Distribution Coefficient, logD

4.080

Water Solubility, LogSw

-4.04

Polar Surface Area

57.751

Acid Dissociation Constant (pKa)

21.04

Base Dissociation Constant (pKb)

5.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L532-2112 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L532-2112 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L532-2112?
Check Price and Availability of L532-2112, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L532-2112 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L532-2112
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L532-2112
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L532-2112 available by request