L537-0407 Screening compound: 1-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-methylpiperidine

L537-0407 Screening compound: 1-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-methylpiperidine
L537-0407 Screening compound: 1-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-methylpiperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L537-0407
1-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-methylpiperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L537-0407

Molecular Formula

C25H28FN3O2 (C25 H28 FN3 O2)

Compound Name

1-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-methylpiperidine

IUPAC name

1-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-methylpiperidine

SMILES

CC(CC1)CCN1C(c1ccc(-c2c(-c(cc3)ccc3F)ncn2C2CCCC2)o1)=O

InChI

InChI=1S/C25H28FN3O2/c1-17-12-14-28(15-13-17)25(30)22-11-10-21(31-22)24-23(18-6-8-19(26)9-7-18)27-16-29(24)20-4-2-3-5-20/h6-11,16-17,20H,2-5,12-15H2,1H3

InChI Key

PWPKPJBNUIRZFG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27460446

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.987

Distribution Coefficient, logD

4.985

Water Solubility, LogSw

-4.63

Polar Surface Area

36.168

Acid Dissociation Constant (pKa)

22.40

Base Dissociation Constant (pKb)

5.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

L537-0407 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L537-0407 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L537-0407?
Check Price and Availability of L537-0407, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L537-0407 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L537-0407
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L537-0407
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L537-0407 available by request