L553-1859 Screening compound: 3-[4-(3,5-dimethylpiperidin-1-yl)-3-methyl-[1,2]oxazolo[5,4-d]pyrimidin-6-yl]-N-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]propanamide

L553-1859 Screening compound: 3-[4-(3,5-dimethylpiperidin-1-yl)-3-methyl-[1,2]oxazolo[5,4-d]pyrimidin-6-yl]-N-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]propanamide
L553-1859 Screening compound: 3-[4-(3,5-dimethylpiperidin-1-yl)-3-methyl-[1,2]oxazolo[5,4-d]pyrimidin-6-yl]-N-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L553-1859
3-[4-(3,5-dimethylpiperidin-1-yl)-3-methyl-[1,2]oxazolo[5,4-d]pyrimidin-6-yl]-N-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L553-1859

Molecular Formula

C28H38N6O2 (C28 H38 N6 O2)

Compound Name

3-[4-(3,5-dimethylpiperidin-1-yl)-3-methyl-[1,2]oxazolo[5,4-d]pyrimidin-6-yl]-N-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]propanamide

IUPAC name

3-[4-(35-dimethylpiperidin-1-yl)-3-methyl-[12]oxazolo[54-d]pyrimidin-6-yl]-N-[3-(1234-tetrahydroisoquinolin-2-yl)propyl]propanamide

SMILES

CC(CC(C)C1)CN1c1c(c(C)no2)c2nc(CCC(NCCCN(CC2)Cc3c2cccc3)=O)n1

InChI

InChI=1S/C28H38N6O2/c1-19-15-20(2)17-34(16-19)27-26-21(3)32-36-28(26)31-24(30-27)9-10-25(35)29-12-6-13-33-14-11-22-7-4-5-8-23(22)18-33/h4-5,7-8,19-20H,6,9-18H2,1-3H3,(H,29,35)

InChI Key

GWHRLDRXURZVQH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27461511

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.65

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.984

Distribution Coefficient, logD

2.780

Water Solubility, LogSw

-4.12

Polar Surface Area

72.917

Acid Dissociation Constant (pKa)

15.38

Base Dissociation Constant (pKb)

8.58

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

57.10

L553-1859 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L553-1859 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L553-1859?
Check Price and Availability of L553-1859, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L553-1859 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L553-1859
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L553-1859
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L553-1859 available by request