L575-0836 Screening compound: 5-(3-{[(2H-1,3-benzodioxol-5-yl)methyl]carbamoyl}propanoyl)-1-methyl-N-phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carboxamide

L575-0836 Screening compound: 5-(3-{[(2H-1,3-benzodioxol-5-yl)methyl]carbamoyl}propanoyl)-1-methyl-N-phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carboxamide
L575-0836 Screening compound: 5-(3-{[(2H-1,3-benzodioxol-5-yl)methyl]carbamoyl}propanoyl)-1-methyl-N-phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L575-0836
5-(3-{[(2H-1,3-benzodioxol-5-yl)methyl]carbamoyl}propanoyl)-1-methyl-N-phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L575-0836

Molecular Formula

C26H27N5O5 (C26 H27 N5 O5)

Compound Name

5-(3-{[(2H-1,3-benzodioxol-5-yl)methyl]carbamoyl}propanoyl)-1-methyl-N-phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carboxamide

IUPAC name

5-(3-{[(2H-13-benzodioxol-5-yl)methyl]carbamoyl}propanoyl)-1-methyl-N-phenyl-1H4H5H6H7H-pyrazolo[43-c]pyridine-3-carboxamide

SMILES

Cn1nc(C(Nc2ccccc2)=O)c(C2)c1CCN2C(CCC(NCc(cc1)cc2c1OCO2)=O)=O

InChI

InChI=1S/C26H27N5O5/c1-30-20-11-12-31(15-19(20)25(29-30)26(34)28-18-5-3-2-4-6-18)24(33)10-9-23(32)27-14-17-7-8-21-22(13-17)36-16-35-21/h2-8,13H,9-12,14-16H2,1H3,(H,27,32)(H,28,34)

InChI Key

QFYBZJCZGNMPCK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27463628

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.53

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.233

Distribution Coefficient, logD

1.233

Water Solubility, LogSw

-2.39

Polar Surface Area

95.717

Acid Dissociation Constant (pKa)

11.40

Base Dissociation Constant (pKb)

1.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.80

L575-0836 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L575-0836 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L575-0836?
Check Price and Availability of L575-0836, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L575-0836 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L575-0836
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L575-0836
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L575-0836 available by request