L583-0355 Screening compound: N-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]furan-2-carboxamide

L583-0355 Screening compound: N-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]furan-2-carboxamide
L583-0355 Screening compound: N-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L583-0355
N-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L583-0355

Molecular Formula

C18H16FN3O3 (C18 H16 FN3 O3)

Compound Name

N-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]furan-2-carboxamide

IUPAC name

N-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]furan-2-carboxamide

SMILES

O=C(c1ccco1)Nc1cc2ccc(N3CCOCC3)nc2c(F)c1

InChI

InChI=1S/C18H16FN3O3/c19-14-11-13(20-18(23)15-2-1-7-25-15)10-12-3-4-16(21-17(12)14)22-5-8-24-9-6-22/h1-4,7,10-11H,5-6,8-9H2,(H,20,23)

InChI Key

HTNMVAPQOMHTPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15131145

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

341.34

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.190

Distribution Coefficient, logD

3.188

Water Solubility, LogSw

-3.41

Polar Surface Area

51.834

Acid Dissociation Constant (pKa)

9.90

Base Dissociation Constant (pKb)

3.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

L583-0355 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with L583-0355 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L583-0355?
Check Price and Availability of L583-0355, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L583-0355 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L583-0355
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L583-0355
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L583-0355 available by request