L604-0659 Screening compound: ethyl 3-{[(3-{5-[(4-methylphenyl)methyl]-1,3,4-oxadiazol-2-yl}phenyl)carbamoyl]amino}propanoate

L604-0659 Screening compound: ethyl 3-{[(3-{5-[(4-methylphenyl)methyl]-1,3,4-oxadiazol-2-yl}phenyl)carbamoyl]amino}propanoate
L604-0659 Screening compound: ethyl 3-{[(3-{5-[(4-methylphenyl)methyl]-1,3,4-oxadiazol-2-yl}phenyl)carbamoyl]amino}propanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L604-0659
ethyl 3-{[(3-{5-[(4-methylphenyl)methyl]-1,3,4-oxadiazol-2-yl}phenyl)carbamoyl]amino}propanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L604-0659

Molecular Formula

C22H24N4O4 (C22 H24 N4 O4)

Compound Name

ethyl 3-{[(3-{5-[(4-methylphenyl)methyl]-1,3,4-oxadiazol-2-yl}phenyl)carbamoyl]amino}propanoate

IUPAC name

ethyl 3-{[(3-{5-[(4-methylphenyl)methyl]-134-oxadiazol-2-yl}phenyl)carbamoyl]amino}propanoate

SMILES

CCOC(CCNC(Nc1cc(-c2nnc(Cc3ccc(C)cc3)o2)ccc1)=O)=O

InChI

InChI=1S/C22H24N4O4/c1-3-29-20(27)11-12-23-22(28)24-18-6-4-5-17(14-18)21-26-25-19(30-21)13-16-9-7-15(2)8-10-16/h4-10,14H,3,11-13H2,1-2H3,(H2,23,24,28)

InChI Key

KYFHYDHCDBWYHL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27464786

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.597

Distribution Coefficient, logD

3.597

Water Solubility, LogSw

-3.63

Polar Surface Area

84.045

Acid Dissociation Constant (pKa)

14.30

Base Dissociation Constant (pKb)

-0.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L604-0659 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Lipid Metabolism Library (9174 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L604-0659 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L604-0659?
Check Price and Availability of L604-0659, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L604-0659 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L604-0659
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L604-0659
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L604-0659 available by request