L612-0256 Screening compound: N-cyclopropyl-6-[(4-{[(2,5-dimethoxyphenyl)sulfonyl]amino}phenyl)sulfanyl]nicotinamide

L612-0256 Screening compound: N-cyclopropyl-6-[(4-{[(2,5-dimethoxyphenyl)sulfonyl]amino}phenyl)sulfanyl]nicotinamide
L612-0256 Screening compound: N-cyclopropyl-6-[(4-{[(2,5-dimethoxyphenyl)sulfonyl]amino}phenyl)sulfanyl]nicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L612-0256
N-cyclopropyl-6-[(4-{[(2,5-dimethoxyphenyl)sulfonyl]amino}phenyl)sulfanyl]nicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L612-0256

Molecular Formula

C23H23N3O5S2 (C23 H23 N3 O5 S2)

Compound Name

N-cyclopropyl-6-[(4-{[(2,5-dimethoxyphenyl)sulfonyl]amino}phenyl)sulfanyl]nicotinamide

IUPAC name

N-cyclopropyl-6-{[4-(25-dimethoxybenzenesulfonamido)phenyl]sulfanyl}pyridine-3-carboxamide

SMILES

COc(cc1)cc(S(Nc(cc2)ccc2Sc(cc2)ncc2C(NC2CC2)=O)(=O)=O)c1OC

InChI

InChI=1S/C23H23N3O5S2/c1-30-18-8-11-20(31-2)21(13-18)33(28,29)26-17-6-9-19(10-7-17)32-22-12-3-15(14-24-22)23(27)25-16-4-5-16/h3,6-14,16,26H,4-5H2,1-2H3,(H,25,27)

InChI Key

QZGCWCRTEGPQFJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15132323

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.58

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.850

Distribution Coefficient, logD

3.842

Water Solubility, LogSw

-4.05

Polar Surface Area

88.759

Acid Dissociation Constant (pKa)

9.15

Base Dissociation Constant (pKb)

1.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.74

L612-0256 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Digestive system
  • Nervous system
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L612-0256 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L612-0256?
Check Price and Availability of L612-0256, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L612-0256 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L612-0256
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L612-0256
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L612-0256 available by request