L614-0259 Screening compound: 1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(prop-2-en-1-yl)pyrrolidine-2-carboxamide

L614-0259 Screening compound: 1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(prop-2-en-1-yl)pyrrolidine-2-carboxamide
L614-0259 Screening compound: 1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(prop-2-en-1-yl)pyrrolidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L614-0259
1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(prop-2-en-1-yl)pyrrolidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L614-0259

Molecular Formula

C22H25N3O5S (C22 H25 N3 O5 S)

Compound Name

1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(prop-2-en-1-yl)pyrrolidine-2-carboxamide

IUPAC name

1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(prop-2-en-1-yl)pyrrolidine-2-carboxamide

SMILES

COc1cccc(S(Nc(cc2)ccc2C(N(CCC2)C2C(NCC=C)=O)=O)(=O)=O)c1

InChI

InChI=1S/C22H25N3O5S/c1-3-13-23-21(26)20-8-5-14-25(20)22(27)16-9-11-17(12-10-16)24-31(28,29)19-7-4-6-18(15-19)30-2/h3-4,6-7,9-12,15,20,24H,1,5,8,13-14H2,2H3,(H,23,26)/t20-/m0/s1

InChI Key

JMCNHEVPEHKEQA-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27466086

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.52

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.031

Distribution Coefficient, logD

1.567

Water Solubility, LogSw

-2.76

Polar Surface Area

89.666

Acid Dissociation Constant (pKa)

7.12

Base Dissociation Constant (pKb)

-0.64

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.30

L614-0259 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L614-0259 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L614-0259?
Check Price and Availability of L614-0259, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L614-0259 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L614-0259
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L614-0259
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L614-0259 available by request