L614-0281 Screening compound: N~2~-cyclopropyl-1-(4-{[(4-methoxyphenyl)sulfonyl]amino}benzoyl)-2-pyrrolidinecarboxamide

L614-0281 Screening compound: N~2~-cyclopropyl-1-(4-{[(4-methoxyphenyl)sulfonyl]amino}benzoyl)-2-pyrrolidinecarboxamide
L614-0281 Screening compound: N~2~-cyclopropyl-1-(4-{[(4-methoxyphenyl)sulfonyl]amino}benzoyl)-2-pyrrolidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L614-0281
N~2~-cyclopropyl-1-(4-{[(4-methoxyphenyl)sulfonyl]amino}benzoyl)-2-pyrrolidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L614-0281

Molecular Formula

C22H25N3O5S (C22 H25 N3 O5 S)

Compound Name

N~2~-cyclopropyl-1-(4-{[(4-methoxyphenyl)sulfonyl]amino}benzoyl)-2-pyrrolidinecarboxamide

IUPAC name

n/a

SMILES

COc(cc1)ccc1S(Nc(cc1)ccc1C(N(CCC1)C1C(NC1CC1)=O)=O)(=O)=O

InChI

InChI=1S/C22H25N3O5S/c1-30-18-10-12-19(13-11-18)31(28,29)24-17-6-4-15(5-7-17)22(27)25-14-2-3-20(25)21(26)23-16-8-9-16/h4-7,10-13,16,20,24H,2-3,8-9,14H2,1H3,(H,23,26)/t20-/m0/s1

InChI Key

QCCCLVUQMXLRGG-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27466099

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.52

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.184

Distribution Coefficient, logD

1.979

Water Solubility, LogSw

-2.73

Polar Surface Area

89.610

Acid Dissociation Constant (pKa)

7.62

Base Dissociation Constant (pKb)

-0.86

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.40

L614-0281 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L614-0281 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L614-0281?
Check Price and Availability of L614-0281, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L614-0281 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L614-0281
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L614-0281
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L614-0281 available by request