L627-1034 Screening compound: N,N-DIMETHYL-4-{[1-METHYL-3-(1-PYRROLIDINYLCARBONYL)-1,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDIN-5-YL]METHYL}BENZAMIDE

L627-1034 Screening compound: N,N-DIMETHYL-4-{[1-METHYL-3-(1-PYRROLIDINYLCARBONYL)-1,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDIN-5-YL]METHYL}BENZAMIDE
L627-1034 Screening compound: N,N-DIMETHYL-4-{[1-METHYL-3-(1-PYRROLIDINYLCARBONYL)-1,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDIN-5-YL]METHYL}BENZAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L627-1034
N,N-DIMETHYL-4-{[1-METHYL-3-(1-PYRROLIDINYLCARBONYL)-1,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDIN-5-YL]METHYL}BENZAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L627-1034

Molecular Formula

C22H29N5O2 (C22 H29 N5 O2)

Compound Name

N,N-DIMETHYL-4-{[1-METHYL-3-(1-PYRROLIDINYLCARBONYL)-1,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDIN-5-YL]METHYL}BENZAMIDE

IUPAC name

n/a

SMILES

CN(C)C(c1ccc(CN(CC2)Cc3c2n(C)nc3C(N2CCCC2)=O)cc1)=O

InChI

InChI=1S/C22H29N5O2/c1-24(2)21(28)17-8-6-16(7-9-17)14-26-13-10-19-18(15-26)20(23-25(19)3)22(29)27-11-4-5-12-27/h6-9H,4-5,10-15H2,1-3H3

InChI Key

YDJVVMXMZLLPCU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27466121

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.371

Distribution Coefficient, logD

-5.948

Water Solubility, LogSw

-1.52

Polar Surface Area

51.665

Acid Dissociation Constant (pKa)

21.41

Base Dissociation Constant (pKb)

13.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

L627-1034 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

Soluble Diversity Library (15920 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L627-1034 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L627-1034?
Check Price and Availability of L627-1034, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L627-1034 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L627-1034
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L627-1034
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L627-1034 available by request