L632-0659 Screening compound: [5-(4-CHLOROBENZOYL)-1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDIN-3-YL][3-(1-PYRROLIDINYLCARBONYL)PIPERIDINO]METHANONE

L632-0659 Screening compound: [5-(4-CHLOROBENZOYL)-1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDIN-3-YL][3-(1-PYRROLIDINYLCARBONYL)PIPERIDINO]METHANONE
L632-0659 Screening compound: [5-(4-CHLOROBENZOYL)-1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDIN-3-YL][3-(1-PYRROLIDINYLCARBONYL)PIPERIDINO]METHANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound L632-0659
[5-(4-CHLOROBENZOYL)-1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDIN-3-YL][3-(1-PYRROLIDINYLCARBONYL)PIPERIDINO]METHANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L632-0659

Molecular Formula

C25H30ClN5O3 (C25 H30 ClN5 O3)

Compound Name

[5-(4-CHLOROBENZOYL)-1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDIN-3-YL][3-(1-PYRROLIDINYLCARBONYL)PIPERIDINO]METHANONE

IUPAC name

n/a

SMILES

Cn1nc(C(N(CCC2)CC2C(N2CCCC2)=O)=O)c(C2)c1CCN2C(c(cc1)ccc1Cl)=O

InChI

InChI=1S/C25H30ClN5O3/c1-28-21-10-14-31(23(32)17-6-8-19(26)9-7-17)16-20(21)22(27-28)25(34)30-13-4-5-18(15-30)24(33)29-11-2-3-12-29/h6-9,18H,2-5,10-16H2,1H3/t18-/m0/s1

InChI Key

OLZOQDGCEKAKEP-SFHVURJKSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.698

Distribution Coefficient, logD

1.698

Water Solubility, LogSw

-2.74

Polar Surface Area

65.162

Acid Dissociation Constant (pKa)

20.78

Base Dissociation Constant (pKb)

0.91

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.00

L632-0659 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L632-0659 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L632-0659?
Check Price and Availability of L632-0659, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L632-0659 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L632-0659
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L632-0659
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L632-0659 available by request