L637-0580 Screening compound: N-[(4-chlorophenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

L637-0580 Screening compound: N-[(4-chlorophenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide
L637-0580 Screening compound: N-[(4-chlorophenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L637-0580
N-[(4-chlorophenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L637-0580

Molecular Formula

C20H19ClN4O2S (C20 H19 ClN4 O2 S)

Compound Name

N-[(4-chlorophenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-1,3-thiazole-4-carboxamide

IUPAC name

N-[(4-chlorophenyl)methyl]-2-[2-(morpholin-4-yl)pyridin-4-yl]-13-thiazole-4-carboxamide

SMILES

O=C(c1csc(-c2cc(N3CCOCC3)ncc2)n1)NCc(cc1)ccc1Cl

InChI

InChI=1S/C20H19ClN4O2S/c21-16-3-1-14(2-4-16)12-23-19(26)17-13-28-20(24-17)15-5-6-22-18(11-15)25-7-9-27-10-8-25/h1-6,11,13H,7-10,12H2,(H,23,26)

InChI Key

UCARHATUYQQCCP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27466941

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.92

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.180

Distribution Coefficient, logD

4.171

Water Solubility, LogSw

-4.58

Polar Surface Area

54.258

Acid Dissociation Constant (pKa)

12.61

Base Dissociation Constant (pKb)

5.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L637-0580 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with L637-0580 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L637-0580?
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What is the minimum amount of L637-0580 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L637-0580
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L637-0580
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L637-0580 available by request