L656-0058 Screening compound: 4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[4-(2,3-dimethylphenyl)piperazin-1-yl]pyrimidine

L656-0058 Screening compound: 4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[4-(2,3-dimethylphenyl)piperazin-1-yl]pyrimidine
L656-0058 Screening compound: 4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[4-(2,3-dimethylphenyl)piperazin-1-yl]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L656-0058
4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[4-(2,3-dimethylphenyl)piperazin-1-yl]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L656-0058

Molecular Formula

C21H26N6 (C21 H26 N6)

Compound Name

4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[4-(2,3-dimethylphenyl)piperazin-1-yl]pyrimidine

IUPAC name

4-(35-dimethyl-1H-pyrazol-1-yl)-6-[4-(23-dimethylphenyl)piperazin-1-yl]pyrimidine

SMILES

Cc1cc(C)nn1-c1cc(N(CC2)CCN2c2c(C)c(C)ccc2)ncn1

InChI

InChI=1S/C21H26N6/c1-15-6-5-7-19(18(15)4)25-8-10-26(11-9-25)20-13-21(23-14-22-20)27-17(3)12-16(2)24-27/h5-7,12-14H,8-11H2,1-4H3

InChI Key

BEOUZLXCRMNSHV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27467497

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

362.48

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.831

Distribution Coefficient, logD

4.826

Water Solubility, LogSw

-4.65

Polar Surface Area

39.259

Acid Dissociation Constant (pKa)

22.49

Base Dissociation Constant (pKb)

5.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

L656-0058 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L656-0058 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L656-0058?
Check Price and Availability of L656-0058, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L656-0058 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L656-0058
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L656-0058
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L656-0058 available by request