L657-0194 Screening compound: N-[3-(2-ethylpiperidino)propyl]-2-(2-thienyl)isonicotinamide

L657-0194 Screening compound: N-[3-(2-ethylpiperidino)propyl]-2-(2-thienyl)isonicotinamide
L657-0194 Screening compound: N-[3-(2-ethylpiperidino)propyl]-2-(2-thienyl)isonicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L657-0194
N-[3-(2-ethylpiperidino)propyl]-2-(2-thienyl)isonicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L657-0194

Molecular Formula

C20H27N3OS (C20 H27 N3 OS)

Compound Name

N-[3-(2-ethylpiperidino)propyl]-2-(2-thienyl)isonicotinamide

IUPAC name

N-[3-(2-ethylpiperidin-1-yl)propyl]-2-(thiophen-2-yl)pyridine-4-carboxamide

SMILES

CCC1N(CCCNC(c2cc(-c3cccs3)ncc2)=O)CCCC1

InChI

InChI=1S/C20H27N3OS/c1-2-17-7-3-4-12-23(17)13-6-10-22-20(24)16-9-11-21-18(15-16)19-8-5-14-25-19/h5,8-9,11,14-15,17H,2-4,6-7,10,12-13H2,1H3,(H,22,24)/t17-/m0/s1

InChI Key

FRFFCKDKAUUFMM-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27467577

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.465

Distribution Coefficient, logD

0.598

Water Solubility, LogSw

-3.65

Polar Surface Area

38.082

Acid Dissociation Constant (pKa)

13.95

Base Dissociation Constant (pKb)

10.27

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

L657-0194 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L657-0194 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L657-0194?
Check Price and Availability of L657-0194, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L657-0194 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L657-0194
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L657-0194
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L657-0194 available by request