L657-0385 Screening compound: 1-[2-(5-methylthiophen-2-yl)pyridine-4-carbonyl]-4-(pyridin-2-yl)piperazine

L657-0385 Screening compound: 1-[2-(5-methylthiophen-2-yl)pyridine-4-carbonyl]-4-(pyridin-2-yl)piperazine
L657-0385 Screening compound: 1-[2-(5-methylthiophen-2-yl)pyridine-4-carbonyl]-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L657-0385
1-[2-(5-methylthiophen-2-yl)pyridine-4-carbonyl]-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L657-0385

Molecular Formula

C20H20N4OS (C20 H20 N4 OS)

Compound Name

1-[2-(5-methylthiophen-2-yl)pyridine-4-carbonyl]-4-(pyridin-2-yl)piperazine

IUPAC name

1-[2-(5-methylthiophen-2-yl)pyridine-4-carbonyl]-4-(pyridin-2-yl)piperazine

SMILES

Cc1ccc(-c2nccc(C(N(CC3)CCN3c3ncccc3)=O)c2)s1

InChI

InChI=1S/C20H20N4OS/c1-15-5-6-18(26-15)17-14-16(7-9-21-17)20(25)24-12-10-23(11-13-24)19-4-2-3-8-22-19/h2-9,14H,10-13H2,1H3

InChI Key

DAIDSKPMDFHXLP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27467615

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.697

Distribution Coefficient, logD

3.688

Water Solubility, LogSw

-3.83

Polar Surface Area

38.453

Acid Dissociation Constant (pKa)

24.69

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L657-0385 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with L657-0385 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L657-0385?
Check Price and Availability of L657-0385, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L657-0385 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L657-0385
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L657-0385
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L657-0385 available by request