L659-0644 Screening compound: 2,4,6-trimethyl-N-[3-(4-oxo-1,3-thiazolidin-2-yl)phenyl]benzene-1-sulfonamide

L659-0644 Screening compound: 2,4,6-trimethyl-N-[3-(4-oxo-1,3-thiazolidin-2-yl)phenyl]benzene-1-sulfonamide
L659-0644 Screening compound: 2,4,6-trimethyl-N-[3-(4-oxo-1,3-thiazolidin-2-yl)phenyl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L659-0644
2,4,6-trimethyl-N-[3-(4-oxo-1,3-thiazolidin-2-yl)phenyl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L659-0644

Molecular Formula

C18H20N2O3S2 (C18 H20 N2 O3 S2)

Compound Name

2,4,6-trimethyl-N-[3-(4-oxo-1,3-thiazolidin-2-yl)phenyl]benzene-1-sulfonamide

IUPAC name

246-trimethyl-N-[3-(4-oxo-13-thiazolidin-2-yl)phenyl]benzene-1-sulfonamide

SMILES

Cc(cc1C)cc(C)c1S(Nc1cc(C(N2)SCC2=O)ccc1)(=O)=O

InChI

InChI=1S/C18H20N2O3S2/c1-11-7-12(2)17(13(3)8-11)25(22,23)20-15-6-4-5-14(9-15)18-19-16(21)10-24-18/h4-9,18,20H,10H2,1-3H3,(H,19,21)/t18-/m0/s1

InChI Key

PETGUPBSDQTIBP-SFHVURJKSA-N

MDL Number (MFCD)

MFCD15132815

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.918

Distribution Coefficient, logD

3.575

Water Solubility, LogSw

-3.83

Polar Surface Area

65.765

Acid Dissociation Constant (pKa)

7.32

Base Dissociation Constant (pKb)

-9.18

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.80

L659-0644 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Digestive system
  • Nervous system
Targets:
  • Nuclear receptors
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L659-0644 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L659-0644?
Check Price and Availability of L659-0644, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L659-0644 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L659-0644
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L659-0644
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L659-0644 available by request