L662-0621 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{[2-(4-fluorophenyl)pyrimidin-4-yl]oxy}benzamide

L662-0621 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{[2-(4-fluorophenyl)pyrimidin-4-yl]oxy}benzamide
L662-0621 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{[2-(4-fluorophenyl)pyrimidin-4-yl]oxy}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L662-0621
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{[2-(4-fluorophenyl)pyrimidin-4-yl]oxy}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L662-0621

Molecular Formula

C25H18FN3O4 (C25 H18 FN3 O4)

Compound Name

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{[2-(4-fluorophenyl)pyrimidin-4-yl]oxy}benzamide

IUPAC name

N-(23-dihydro-14-benzodioxin-6-yl)-4-{[2-(4-fluorophenyl)pyrimidin-4-yl]oxy}benzamide

SMILES

O=C(c(cc1)ccc1Oc1ccnc(-c(cc2)ccc2F)n1)Nc(cc1)cc2c1OCCO2

InChI

InChI=1S/C25H18FN3O4/c26-18-5-1-16(2-6-18)24-27-12-11-23(29-24)33-20-8-3-17(4-9-20)25(30)28-19-7-10-21-22(15-19)32-14-13-31-21/h1-12,15H,13-14H2,(H,28,30)

InChI Key

ITKJPXSENAZACU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27467729

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.607

Distribution Coefficient, logD

3.606

Water Solubility, LogSw

-3.78

Polar Surface Area

64.533

Acid Dissociation Constant (pKa)

10.21

Base Dissociation Constant (pKb)

2.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.00

L662-0621 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with L662-0621 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L662-0621?
Check Price and Availability of L662-0621, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L662-0621 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L662-0621
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L662-0621
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L662-0621 available by request