L703-5844 Screening compound: 5-chloro-2-{4-[5-(2-methoxyphenyl)-1,2,4-oxadiazol-3-yl]piperidine-1-carbonyl}-1H-indole

L703-5844 Screening compound: 5-chloro-2-{4-[5-(2-methoxyphenyl)-1,2,4-oxadiazol-3-yl]piperidine-1-carbonyl}-1H-indole
L703-5844 Screening compound: 5-chloro-2-{4-[5-(2-methoxyphenyl)-1,2,4-oxadiazol-3-yl]piperidine-1-carbonyl}-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound L703-5844
5-chloro-2-{4-[5-(2-methoxyphenyl)-1,2,4-oxadiazol-3-yl]piperidine-1-carbonyl}-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L703-5844

Molecular Formula

C23H21ClN4O3 (C23 H21 ClN4 O3)

Compound Name

5-chloro-2-{4-[5-(2-methoxyphenyl)-1,2,4-oxadiazol-3-yl]piperidine-1-carbonyl}-1H-indole

IUPAC name

5-chloro-2-{4-[5-(2-methoxyphenyl)-124-oxadiazol-3-yl]piperidine-1-carbonyl}-1H-indole

SMILES

COc(cccc1)c1-c1nc(C(CC2)CCN2C(c2cc(cc(cc3)Cl)c3[nH]2)=O)no1

InChI

InChI=1S/C23H21ClN4O3/c1-30-20-5-3-2-4-17(20)22-26-21(27-31-22)14-8-10-28(11-9-14)23(29)19-13-15-12-16(24)6-7-18(15)25-19/h2-7,12-14,25H,8-11H2,1H3

InChI Key

ACYIDOUODAIODC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27471476

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.9

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.895

Distribution Coefficient, logD

4.895

Water Solubility, LogSw

-4.90

Polar Surface Area

65.272

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

-0.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

L703-5844 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L703-5844 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L703-5844?
Check Price and Availability of L703-5844, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L703-5844 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L703-5844
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L703-5844
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L703-5844 available by request