L710-0370 Screening compound: 8-{5-[2-(piperidine-1-carbonyl)phenyl]-1,3-oxazole-4-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

L710-0370 Screening compound: 8-{5-[2-(piperidine-1-carbonyl)phenyl]-1,3-oxazole-4-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane
L710-0370 Screening compound: 8-{5-[2-(piperidine-1-carbonyl)phenyl]-1,3-oxazole-4-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound L710-0370
8-{5-[2-(piperidine-1-carbonyl)phenyl]-1,3-oxazole-4-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L710-0370

Molecular Formula

C23H27N3O5 (C23 H27 N3 O5)

Compound Name

8-{5-[2-(piperidine-1-carbonyl)phenyl]-1,3-oxazole-4-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-{5-[2-(piperidine-1-carbonyl)phenyl]-13-oxazole-4-carbonyl}-14-dioxa-8-azaspiro[4.5]decane

SMILES

O=C(c1c(-c(cccc2)c2C(N2CCCCC2)=O)ocn1)N(CC1)CCC11OCCO1

InChI

InChI=1S/C23H27N3O5/c27-21(25-10-4-1-5-11-25)18-7-3-2-6-17(18)20-19(24-16-29-20)22(28)26-12-8-23(9-13-26)30-14-15-31-23/h2-3,6-7,16H,1,4-5,8-15H2

InChI Key

QEPLQBHKUDEHBW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27472515

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

425.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.566

Distribution Coefficient, logD

1.566

Water Solubility, LogSw

-2.05

Polar Surface Area

66.808

Acid Dissociation Constant (pKa)

27.37

Base Dissociation Constant (pKb)

-2.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.20

L710-0370 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with L710-0370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L710-0370?
Check Price and Availability of L710-0370, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L710-0370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L710-0370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L710-0370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L710-0370 available by request