L718-0126 Screening compound: ethyl 2-[4-({[1-(benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]carbamoyl}amino)phenyl]acetate

L718-0126 Screening compound: ethyl 2-[4-({[1-(benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]carbamoyl}amino)phenyl]acetate
L718-0126 Screening compound: ethyl 2-[4-({[1-(benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]carbamoyl}amino)phenyl]acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L718-0126
ethyl 2-[4-({[1-(benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]carbamoyl}amino)phenyl]acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L718-0126

Molecular Formula

C25H25N3O5S (C25 H25 N3 O5 S)

Compound Name

ethyl 2-[4-({[1-(benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]carbamoyl}amino)phenyl]acetate

IUPAC name

ethyl 2-[4-({[1-(benzenesulfonyl)-23-dihydro-1H-indol-5-yl]carbamoyl}amino)phenyl]acetate

SMILES

CCOC(Cc(cc1)ccc1NC(Nc(cc1)cc(CC2)c1N2S(c1ccccc1)(=O)=O)=O)=O

InChI

InChI=1S/C25H25N3O5S/c1-2-33-24(29)16-18-8-10-20(11-9-18)26-25(30)27-21-12-13-23-19(17-21)14-15-28(23)34(31,32)22-6-4-3-5-7-22/h3-13,17H,2,14-16H2,1H3,(H2,26,27,30)

InChI Key

QPXDSUQEIVXIAT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15133951

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.56

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.324

Distribution Coefficient, logD

4.324

Water Solubility, LogSw

-4.14

Polar Surface Area

84.219

Acid Dissociation Constant (pKa)

13.25

Base Dissociation Constant (pKb)

1.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

L718-0126 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Regenerative Medicine Focused Library (23016 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L718-0126 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L718-0126?
Check Price and Availability of L718-0126, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L718-0126 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L718-0126
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L718-0126
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L718-0126 available by request