L718-0131 Screening compound: ethyl 2-({[1-(benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]carbamoyl}amino)acetate

L718-0131 Screening compound: ethyl 2-({[1-(benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]carbamoyl}amino)acetate
L718-0131 Screening compound: ethyl 2-({[1-(benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]carbamoyl}amino)acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L718-0131
ethyl 2-({[1-(benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]carbamoyl}amino)acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L718-0131

Molecular Formula

C19H21N3O5S (C19 H21 N3 O5 S)

Compound Name

ethyl 2-({[1-(benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]carbamoyl}amino)acetate

IUPAC name

ethyl 2-({[1-(benzenesulfonyl)-23-dihydro-1H-indol-5-yl]carbamoyl}amino)acetate

SMILES

CCOC(CNC(Nc(cc1)cc(CC2)c1N2S(c1ccccc1)(=O)=O)=O)=O

InChI

InChI=1S/C19H21N3O5S/c1-2-27-18(23)13-20-19(24)21-15-8-9-17-14(12-15)10-11-22(17)28(25,26)16-6-4-3-5-7-16/h3-9,12H,2,10-11,13H2,1H3,(H2,20,21,24)

InChI Key

LWLNGZQNRLHGRK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15133954

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.46

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.306

Distribution Coefficient, logD

2.306

Water Solubility, LogSw

-2.98

Polar Surface Area

85.812

Acid Dissociation Constant (pKa)

13.45

Base Dissociation Constant (pKb)

1.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

L718-0131 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L718-0131 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L718-0131?
Check Price and Availability of L718-0131, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L718-0131 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L718-0131
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L718-0131
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L718-0131 available by request