L740-0321 Screening compound: 2-(6-BENZYL-2-METHYL-5,7-DIOXO-2,5,6,7-TETRAHYDRO-4H-PYRAZOLO[4,3-D]PYRIMIDIN-4-YL)-N-(2,5-DIMETHOXYPHENYL)ACETAMIDE

L740-0321 Screening compound: 2-(6-BENZYL-2-METHYL-5,7-DIOXO-2,5,6,7-TETRAHYDRO-4H-PYRAZOLO[4,3-D]PYRIMIDIN-4-YL)-N-(2,5-DIMETHOXYPHENYL)ACETAMIDE
L740-0321 Screening compound: 2-(6-BENZYL-2-METHYL-5,7-DIOXO-2,5,6,7-TETRAHYDRO-4H-PYRAZOLO[4,3-D]PYRIMIDIN-4-YL)-N-(2,5-DIMETHOXYPHENYL)ACETAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L740-0321
2-(6-BENZYL-2-METHYL-5,7-DIOXO-2,5,6,7-TETRAHYDRO-4H-PYRAZOLO[4,3-D]PYRIMIDIN-4-YL)-N-(2,5-DIMETHOXYPHENYL)ACETAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L740-0321

Molecular Formula

C20H28ClN5O3 (C20 H28 ClN5 O3)

Compound Name

2-(6-BENZYL-2-METHYL-5,7-DIOXO-2,5,6,7-TETRAHYDRO-4H-PYRAZOLO[4,3-D]PYRIMIDIN-4-YL)-N-(2,5-DIMETHOXYPHENYL)ACETAMIDE

IUPAC name

N-(4-chlorophenyl)-3-oxo-4-({[2-(piperidin-1-yl)ethyl]carbamoyl}methyl)piperazine-1-carboxamide

SMILES

O=C(CN(CCN(C1)C(Nc(cc2)ccc2Cl)=O)C1=O)NCCN1CCCCC1

InChI

InChI=1S/C20H28ClN5O3/c21-16-4-6-17(7-5-16)23-20(29)26-13-12-25(19(28)15-26)14-18(27)22-8-11-24-9-2-1-3-10-24/h4-7H,1-3,8-15H2,(H,22,27)(H,23,29)

InChI Key

DMYDJMOGYHHKGY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27473360

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.93

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.138

Distribution Coefficient, logD

-0.372

Water Solubility, LogSw

-2.65

Polar Surface Area

70.641

Acid Dissociation Constant (pKa)

12.24

Base Dissociation Constant (pKb)

8.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.00

L740-0321 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Immune system
Targets:
  • GPCR
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L740-0321 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L740-0321?
Check Price and Availability of L740-0321, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L740-0321 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L740-0321
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L740-0321
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L740-0321 available by request