L767-0247 Screening compound: methyl 3-({[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]carbamoyl}amino)benzoate

L767-0247 Screening compound: methyl 3-({[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]carbamoyl}amino)benzoate
L767-0247 Screening compound: methyl 3-({[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]carbamoyl}amino)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L767-0247
methyl 3-({[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]carbamoyl}amino)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L767-0247

Molecular Formula

C22H22N4O5S2 (C22 H22 N4 O5 S2)

Compound Name

methyl 3-({[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]carbamoyl}amino)benzoate

IUPAC name

methyl 3-({[5-(4-methylbenzenesulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]carbamoyl}amino)benzoate

SMILES

Cc(cc1)ccc1S(N(CC1)Cc2c1nc(NC(Nc1cc(C(OC)=O)ccc1)=O)s2)(=O)=O

InChI

InChI=1S/C22H22N4O5S2/c1-14-6-8-17(9-7-14)33(29,30)26-11-10-18-19(13-26)32-22(24-18)25-21(28)23-16-5-3-4-15(12-16)20(27)31-2/h3-9,12H,10-11,13H2,1-2H3,(H2,23,24,25,28)

InChI Key

GMZQKWLTJLMZTD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474092

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.57

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.950

Distribution Coefficient, logD

4.907

Water Solubility, LogSw

-4.60

Polar Surface Area

96.635

Acid Dissociation Constant (pKa)

8.39

Base Dissociation Constant (pKb)

1.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

L767-0247 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Integrin Receptors Targeted library (1715 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L767-0247 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L767-0247?
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What is the minimum amount of L767-0247 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L767-0247
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L767-0247
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L767-0247 available by request