L810-0480 Screening compound: 4-(3,5-difluorophenyl)-6-fluoro-2-(1-pyrrolidinylcarbonyl)-1lambda~6~,4-benzothiazine-1,1(4H)-dione

L810-0480 Screening compound: 4-(3,5-difluorophenyl)-6-fluoro-2-(1-pyrrolidinylcarbonyl)-1lambda~6~,4-benzothiazine-1,1(4H)-dione
L810-0480 Screening compound: 4-(3,5-difluorophenyl)-6-fluoro-2-(1-pyrrolidinylcarbonyl)-1lambda~6~,4-benzothiazine-1,1(4H)-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L810-0480
4-(3,5-difluorophenyl)-6-fluoro-2-(1-pyrrolidinylcarbonyl)-1lambda~6~,4-benzothiazine-1,1(4H)-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L810-0480

Molecular Formula

C19H15F3N2O3S (C19 H15 F3 N2 O3 S)

Compound Name

4-(3,5-difluorophenyl)-6-fluoro-2-(1-pyrrolidinylcarbonyl)-1lambda~6~,4-benzothiazine-1,1(4H)-dione

IUPAC name

4-(35-difluorophenyl)-6-fluoro-2-(pyrrolidine-1-carbonyl)-4H-1lambda64-benzothiazine-11-dione

SMILES

O=C(C1=CN(c2cc(F)cc(F)c2)c(cc(cc2)F)c2S1(=O)=O)N1CCCC1

InChI

InChI=1S/C19H15F3N2O3S/c20-12-3-4-17-16(10-12)24(15-8-13(21)7-14(22)9-15)11-18(28(17,26)27)19(25)23-5-1-2-6-23/h3-4,7-11H,1-2,5-6H2

InChI Key

PEVMLXQFAPBEGG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27476761

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.810

Distribution Coefficient, logD

2.810

Water Solubility, LogSw

-3.39

Polar Surface Area

47.965

Acid Dissociation Constant (pKa)

27.85

Base Dissociation Constant (pKb)

-3.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

L810-0480 in Drug Discovery

Included in Screening Libraries

Nucleic Acid Ligands (8311 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L810-0480 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L810-0480?
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What is the minimum amount of L810-0480 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L810-0480
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L810-0480
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L810-0480 available by request