L826-1246 Screening compound: ethyl 4-(3-{3-[4-(dimethylamino)phenyl]-1,2,4-oxadiazol-5-yl}propanamido)benzoate

L826-1246 Screening compound: ethyl 4-(3-{3-[4-(dimethylamino)phenyl]-1,2,4-oxadiazol-5-yl}propanamido)benzoate
L826-1246 Screening compound: ethyl 4-(3-{3-[4-(dimethylamino)phenyl]-1,2,4-oxadiazol-5-yl}propanamido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L826-1246
ethyl 4-(3-{3-[4-(dimethylamino)phenyl]-1,2,4-oxadiazol-5-yl}propanamido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L826-1246

Molecular Formula

C22H24N4O4 (C22 H24 N4 O4)

Compound Name

ethyl 4-(3-{3-[4-(dimethylamino)phenyl]-1,2,4-oxadiazol-5-yl}propanamido)benzoate

IUPAC name

ethyl 4-(3-{3-[4-(dimethylamino)phenyl]-124-oxadiazol-5-yl}propanamido)benzoate

SMILES

CCOC(c(cc1)ccc1NC(CCc1nc(-c(cc2)ccc2N(C)C)no1)=O)=O

InChI

InChI=1S/C22H24N4O4/c1-4-29-22(28)16-5-9-17(10-6-16)23-19(27)13-14-20-24-21(25-30-20)15-7-11-18(12-8-15)26(2)3/h5-12H,4,13-14H2,1-3H3,(H,23,27)

InChI Key

DJBJAELKMIULPQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27478052

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.395

Distribution Coefficient, logD

4.395

Water Solubility, LogSw

-4.20

Polar Surface Area

78.018

Acid Dissociation Constant (pKa)

10.83

Base Dissociation Constant (pKb)

6.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L826-1246 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SH2 Library (10483 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Cancer
  • Endocrine
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • Epigenetic
  • PPI modulators
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L826-1246 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L826-1246?
Check Price and Availability of L826-1246, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L826-1246 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L826-1246
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L826-1246
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L826-1246 available by request