L827-0131 Screening compound: 1-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-4-(pyridin-2-yl)piperazine

L827-0131 Screening compound: 1-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-4-(pyridin-2-yl)piperazine
L827-0131 Screening compound: 1-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L827-0131
1-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L827-0131

Molecular Formula

C22H20N6O (C22 H20 N6 O)

Compound Name

1-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-4-(pyridin-2-yl)piperazine

IUPAC name

1-[5-(3-phenyl-124-oxadiazol-5-yl)pyridin-2-yl]-4-(pyridin-2-yl)piperazine

SMILES

C(CN(CC1)c(cc2)ncc2-c2nc(-c3ccccc3)no2)N1c1ncccc1

InChI

InChI=1S/C22H20N6O/c1-2-6-17(7-3-1)21-25-22(29-26-21)18-9-10-20(24-16-18)28-14-12-27(13-15-28)19-8-4-5-11-23-19/h1-11,16H,12-15H2

InChI Key

LDEYYFVBUYPDSP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27478144

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.020

Distribution Coefficient, logD

5.006

Water Solubility, LogSw

-4.84

Polar Surface Area

55.469

Acid Dissociation Constant (pKa)

24.54

Base Dissociation Constant (pKb)

5.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

L827-0131 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with L827-0131 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L827-0131?
Check Price and Availability of L827-0131, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L827-0131 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L827-0131
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L827-0131
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L827-0131 available by request