L827-1861 Screening compound: N-[3-(azepan-1-yl)butyl]-5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-amine

L827-1861 Screening compound: N-[3-(azepan-1-yl)butyl]-5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-amine
L827-1861 Screening compound: N-[3-(azepan-1-yl)butyl]-5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L827-1861
N-[3-(azepan-1-yl)butyl]-5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L827-1861

Molecular Formula

C23H28FN5O (C23 H28 FN5 O)

Compound Name

N-[3-(azepan-1-yl)butyl]-5-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-amine

IUPAC name

N-[3-(azepan-1-yl)butyl]-5-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]pyridin-2-amine

SMILES

CC(CCNc(cc1)ncc1-c1nc(-c2cccc(F)c2)no1)N1CCCCCC1

InChI

InChI=1S/C23H28FN5O/c1-17(29-13-4-2-3-5-14-29)11-12-25-21-10-9-19(16-26-21)23-27-22(28-30-23)18-7-6-8-20(24)15-18/h6-10,15-17H,2-5,11-14H2,1H3,(H,25,26)/t17-/m0/s1

InChI Key

ZUZUJSQWBBRMSO-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27478402

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.247

Distribution Coefficient, logD

2.795

Water Solubility, LogSw

-4.89

Polar Surface Area

55.396

Acid Dissociation Constant (pKa)

20.34

Base Dissociation Constant (pKb)

9.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.50

L827-1861 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
  • Kinases
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L827-1861 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L827-1861?
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What is the minimum amount of L827-1861 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L827-1861
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L827-1861
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L827-1861 available by request