L853-0156 Screening compound: 2-ethylphenyl [1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl] sulfone

L853-0156 Screening compound: 2-ethylphenyl [1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl] sulfone
L853-0156 Screening compound: 2-ethylphenyl [1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl] sulfone alternative view

Chemical Structure Depiction of ChemDiv screening compound L853-0156
2-ethylphenyl [1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl] sulfone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L853-0156

Molecular Formula

C18H21N5O3S (C18 H21 N5 O3 S)

Compound Name

2-ethylphenyl [1-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl] sulfone

IUPAC name

n/a

SMILES

CCc(cccc1)c1S(N(CC1)Cc2c1n(C)nc2-c1nc(C)no1)(=O)=O

InChI

InChI=1S/C18H21N5O3S/c1-4-13-7-5-6-8-16(13)27(24,25)23-10-9-15-14(11-23)17(20-22(15)3)18-19-12(2)21-26-18/h5-8H,4,9-11H2,1-3H3

InChI Key

LQGLOBJSAKQSEI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27480570

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.46

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.036

Distribution Coefficient, logD

2.036

Water Solubility, LogSw

-2.40

Polar Surface Area

77.919

Acid Dissociation Constant (pKa)

21.52

Base Dissociation Constant (pKb)

0.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

L853-0156 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L853-0156 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L853-0156?
Check Price and Availability of L853-0156, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L853-0156 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L853-0156
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L853-0156
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L853-0156 available by request