L857-1011 Screening compound: ethyl 4-{1-[4-(morpholin-4-yl)phthalazin-1-yl]piperidine-4-carbonyl}piperazine-1-carboxylate

L857-1011 Screening compound: ethyl 4-{1-[4-(morpholin-4-yl)phthalazin-1-yl]piperidine-4-carbonyl}piperazine-1-carboxylate
L857-1011 Screening compound: ethyl 4-{1-[4-(morpholin-4-yl)phthalazin-1-yl]piperidine-4-carbonyl}piperazine-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound L857-1011
ethyl 4-{1-[4-(morpholin-4-yl)phthalazin-1-yl]piperidine-4-carbonyl}piperazine-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L857-1011

Molecular Formula

C25H34N6O4 (C25 H34 N6 O4)

Compound Name

ethyl 4-{1-[4-(morpholin-4-yl)phthalazin-1-yl]piperidine-4-carbonyl}piperazine-1-carboxylate

IUPAC name

ethyl 4-{1-[4-(morpholin-4-yl)phthalazin-1-yl]piperidine-4-carbonyl}piperazine-1-carboxylate

SMILES

CCOC(N(CC1)CCN1C(C(CC1)CCN1c(c1ccccc11)nnc1N1CCOCC1)=O)=O

InChI

InChI=1S/C25H34N6O4/c1-2-35-25(33)31-13-11-30(12-14-31)24(32)19-7-9-28(10-8-19)22-20-5-3-4-6-21(20)23(27-26-22)29-15-17-34-18-16-29/h3-6,19H,2,7-18H2,1H3

InChI Key

LCWQIBNLRAUIPI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27480871

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.58

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.623

Distribution Coefficient, logD

2.623

Water Solubility, LogSw

-2.60

Polar Surface Area

75.818

Acid Dissociation Constant (pKa)

22.25

Base Dissociation Constant (pKb)

4.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

L857-1011 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L857-1011 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L857-1011?
Check Price and Availability of L857-1011, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L857-1011 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L857-1011
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L857-1011
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L857-1011 available by request